Pabuçcu R, Atay V, Orhon E, Urman B, Ergün A
Department of Obstetrics and Gynecology, Gülhane School of Medicine, Ankara, Turkey.
Fertil Steril. 1997 Dec;68(6):1141-3. doi: 10.1016/s0015-0282(97)00375-0.
To assess the safety and efficacy of hysteroscopic adhesiolysis in patients with recurrent pregnancy loss and infertility.
Retrospective case report series.
The obstetrics and gynecology clinic of a medical school.
PATIENT(S): Forty women with recurrent pregnancy loss or infertility resulting from intrauterine adhesions.
INTERVENTION(S): Hysteroscopic adhesiolysis in patients with recurrent pregnancy loss and infertility.
MAIN OUTCOME MEASURE(S): Postoperative adhesion formation, intraoperative complication, conceivement after surgery, pregnancy rate, and pregnancies resulted in term or viable preterm infants.
RESULT(S): Most patients with minimal or moderate adhesions were free of adhesions when compared with postoperative control subjects. However, adhesion re-formation was noted in 60% of the patients who initially had severe adhesions. Normal menstrual flow was restored in 81% of the patients. All the patients who had recurrent pregnancy loss conceived after treatment, and 71% of the pregnancies resulted in a term or viable preterm infant. Of the 16 infertile patients treated, 10 (63%) conceived and 6 (37%) were delivered of viable infants.
CONCLUSION(S): Hysteroscopic adhesiolysis is a safe and effective procedure for restoring the normal menstrual pattern and fertility. The initial severity of the adhesions appears to correlate best with the reproductive outcome.
评估宫腔镜粘连松解术对复发性流产和不孕症患者的安全性和有效性。
回顾性病例报告系列。
一所医学院的妇产科诊所。
40名因宫腔粘连导致复发性流产或不孕的女性。
对复发性流产和不孕症患者进行宫腔镜粘连松解术。
术后粘连形成、术中并发症、术后受孕情况、妊娠率以及足月或存活早产婴儿的妊娠情况。
与术后对照组相比，大多数轻度或中度粘连患者无粘连。然而，最初有重度粘连的患者中，60%出现了粘连再形成。81%的患者月经恢复正常。所有复发性流产患者治疗后均受孕，71%的妊娠产生了足月或存活早产婴儿。在接受治疗的16名不孕患者中，10名（63%）受孕，6名（37%）分娩出存活婴儿。
宫腔镜粘连松解术是恢复正常月经模式和生育能力的一种安全有效的方法。粘连的初始严重程度似乎与生殖结局的相关性最佳。
