Herdman Anthony T, Wollbrink Andreas, Chau Wilkin, Ishii Ryouhei, Ross Bernhard, Pantev Christo
Rotman Research Institute, Baycrest Centre for Geriatric Care, University of Toronto, Toronto, Canada M6A 2E1.
Neuroimage. 2003 Oct;20(2):995-1005. doi: 10.1016/S1053-8119(03)00403-8.
In this study we applied synthetic aperture magnetometry (SAM) to investigate active cortical areas associated with magnetically recorded transient and steady-state auditory evoked responses. For transient evoked responses, SAM images reveal an activated volume of cortical tissue within the lateral aspect of the superior temporal plane. The volume of cortical activation for steady-state responses was located more medially than that for transient evoked responses. Additionally, SAM also reveals a small overlap of activated areas between transient and steady-state evoked responses, which has not be demonstrated when using equivalent current dipole (ECD) source modeling. Source waveforms from SAM and ECD analyses show comparable temporal information. Results from this study suggest that SAM is a useful technique for imaging cortical structures involved in processing perceptual information.
在本研究中，我们应用合成孔径磁强计（SAM）来研究与磁记录的瞬态和稳态听觉诱发反应相关的活跃皮质区域。对于瞬态诱发反应，SAM图像显示颞上平面外侧的皮质组织有一个激活区域。稳态反应的皮质激活区域比瞬态诱发反应的更靠内侧。此外，SAM还揭示了瞬态和稳态诱发反应之间激活区域的小范围重叠，这在用等效电流偶极子（ECD）源模型时未得到证实。SAM和ECD分析的源波形显示出可比的时间信息。本研究结果表明，SAM是一种用于对参与处理感知信息的皮质结构进行成像的有用技术。
