Janssen Fanny, Nusselder Wilma J, Looman Caspar W N, Mackenbach Johan P, Kunst Anton E
Department of Public Health, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Gerontologist. 2003 Oct;43(5):722-34. doi: 10.1093/geront/43.5.722.
This study assesses whether the stagnation of old-age (80+) mortality decline observed in The Netherlands in the 1980s continued in the 1990s and determines which factors contributed to this stagnation. Emphasis is on the role of smoking.
Poisson regression analysis with linear splines was applied to total and cause-specific mortality data by age, year of death (1950-1999), and sex. An age-period-cohort analysis was carried out to determine whether the trends followed period or cohort patterns. ICD revisions were bridged by use of a concordance table.
A sudden reversal in old-age mortality decline occurred around 1980, leading to a stagnation of the decline and even increases in mortality thereafter. Smoking-related cancers, chronic obstructive pulmonary disease, and diseases specifically related to old age contributed to this stagnation. Trends in smoking-related cancers and chronic obstructive pulmonary disease showed a cohort pattern--especially for men. When these smoking-related diseases were excluded, the trends in old-age mortality in The Netherlands showed an increasing stagnation for both sexes.
Smoking behavior can only partly explain the stagnation of mortality. Other factors such as increased frailty and changes in medical and social services for elderly people probably played a more decisive role in the recent stagnation.
本研究评估了20世纪80年代在荷兰观察到的老年(80岁及以上)死亡率下降停滞现象在20世纪90年代是否持续,并确定了导致这种停滞的因素。重点是吸烟的作用。
采用带线性样条的泊松回归分析,对按年龄、死亡年份(1950 - 1999年)和性别分类的总死亡率及特定病因死亡率数据进行分析。进行年龄 - 时期 - 队列分析以确定趋势遵循时期模式还是队列模式。通过使用一致性表格来衔接国际疾病分类(ICD)的修订版本。
老年死亡率下降在1980年左右突然逆转,导致下降停滞,此后死亡率甚至上升。与吸烟相关的癌症、慢性阻塞性肺疾病以及与老年特别相关的疾病导致了这种停滞。与吸烟相关的癌症和慢性阻塞性肺疾病的趋势呈现队列模式——尤其是男性。当排除这些与吸烟相关的疾病后,荷兰老年死亡率的趋势显示两性都出现了越来越明显的停滞。
吸烟行为只能部分解释死亡率的停滞。其他因素,如老年人身体虚弱加剧以及医疗和社会服务的变化,可能在近期的停滞中起到了更决定性的作用。