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黄疸型肝细胞癌的成功诊断与切除

Successful diagnosis and resection of icteric type hepatocellular carcinoma.

作者信息

Murakami Yoshiaki, Yokoyama Takashi, Kanehiro Tetsuya, Uemura Kenichiro, Sasaki Masaru, Morifuji Masahiko, Sueda Taijiro

机构信息

First Department of Surgery, Hiroshima University, Faculty of Medicine, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

出版信息

Hepatogastroenterology. 2003 Sep-Oct;50(53):1634-6.

Abstract

We report a rare case of icteric type hepatocellular carcinoma with successful preoperative diagnosis and curative resection. A 50-year-old man was admitted to our hospital with fever elevation and jaundice. Endoscopic retrograde cholangiography revealed a tumor at the hepatic hilum, which caused obstruction of the right and left hepatic duct. The tumor was suspected of being a hilar cholangiocarcinoma, but it was diagnosed as being a hepatocellular carcinoma by endoscopic retrograde bile duct biopsy. After percutaneous transhepatic biliary drainage a right hemihepatectomy was performed. Subsequent pathological finding showed the tumor to be moderately-differentiated hepatocellular carcinoma (Edmondson III) which invaded into the right hepatic duct. The patient survived for three years without recurrence. Although patients with icteric type hepatocellular carcinoma have been reported to have a poor prognosis, earlier diagnosis and curative resection may occasionally bring them an improved prognosis.

摘要

我们报告一例黄疸型肝细胞癌的罕见病例,术前诊断成功并进行了根治性切除。一名50岁男性因发热和黄疸入院。内镜逆行胆管造影显示肝门处有肿瘤,导致左右肝管梗阻。该肿瘤疑似肝门部胆管癌,但经内镜逆行胆管活检诊断为肝细胞癌。经皮经肝胆道引流后,进行了右半肝切除术。随后的病理检查显示肿瘤为中度分化肝细胞癌(Edmondson III级),侵犯右肝管。患者存活三年无复发。尽管据报道黄疸型肝细胞癌患者预后较差,但早期诊断和根治性切除偶尔可能会改善他们的预后。

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