Hyodo Masanobu, Nagai Hideo, Sata Naohiro, Ishitsuka Tsuneo, Kurihara Katsumi, Yoshizawa Kohji, Saitoh Ken
Department of Surgery, Jichi Medical School, Minami-Kawachi, Tochigi, 329-0989, Japan.
Hepatogastroenterology. 2003 Sep-Oct;50(53):1687-8.
A 43-year-old Japanese man had an increasing level of serum CEA pointed out by annual physical check-ups. No abnormal findings were detected in the lungs or gastrointestinal tract. The only pathological lesions were a 1.5-cm-sized nodule in the pancreatic tail and a 5-cm-sized thyroid tumor. The thyroid tumor was shown to be medullary carcinoma by aspiration cytology. He underwent total thyroidectomy with extensive lymph node dissection. After thyroid surgery, the patient received distal pancreatectomy 2 weeks later. Pathological examination revealed the pancreatic tumor to be a metastasis of thyroid medullary carcinoma. The patient is alive and well without recurrence 5 years after thyroidectomy and pancreatectomy. The serum levels of CEA and calcitonin remain within normal limits. Thus, the patient seems to have had a solitary metastatic tumor from thyroid medullary cancer.
一名43岁的日本男性在年度体检中发现血清癌胚抗原(CEA)水平不断升高。肺部和胃肠道未发现异常。唯一的病理病变是胰尾有一个1.5厘米大小的结节和一个5厘米大小的甲状腺肿瘤。细针穿刺细胞学检查显示甲状腺肿瘤为髓样癌。他接受了甲状腺全切除术及广泛淋巴结清扫术。甲状腺手术后2周,患者接受了胰体尾切除术。病理检查显示胰腺肿瘤是甲状腺髓样癌的转移灶。甲状腺切除和胰腺切除术后5年,患者存活且状况良好,无复发迹象。CEA和降钙素血清水平仍在正常范围内。因此,该患者似乎患有甲状腺髓样癌的孤立性转移瘤。