Osler M, Christensen U, Lund R, Gamborg M, Godtfredsen N, Prescott E
Department of Social Medicine, Institute of Public Health, University of Copenhagen, Blegdamsvej 3, 2200 N, Denmark.
Occup Environ Med. 2003 Nov;60(11):e16. doi: 10.1136/oem.60.11.e16.
To examine the relation between unemployment rates in area of residence and all-cause mortality, taking the individuals' unemployment experience and a number of social and behavioural factors into account.
Prospective cohort study with record linkage to mortality and unemployment registers. Data were pooled data from two population studies conducted in Copenhagen, Denmark. The association between unemployment at parish level and mortality was examined in Cox proportional hazard analysis. A total of 15 980 men and women, aged 20-67 years and employed at 1 January 1980, were studied. All-cause mortality was followed from January 1981 to December 1998.
The unemployment rate in the area of residence was associated with increased mortality (hazard ratio(highest v lowest quartile) 1.35:0.14-1.60) even after adjustment for individuals' unemployment experience in 1980, which was also a risk factor (hazard ratio(yes/no) 1.38:1.16-1.64). These estimates attenuated somewhat when other social and behavioural covariates were taken into account. The effects were similar in men and women, but the influence of individuals' unemployment experience during one and five years decreased gradually with increasing age.
This prospective study suggests that high local unemployment and individuals' experience of unemployment increase mortality risk, even after adjustment for other social and behavioural factors.
考虑个体的失业经历以及一些社会和行为因素,研究居住地区的失业率与全因死亡率之间的关系。
前瞻性队列研究,与死亡率和失业登记记录相链接。数据来自丹麦哥本哈根进行的两项人群研究的汇总数据。在Cox比例风险分析中检验教区层面的失业率与死亡率之间的关联。共研究了15980名年龄在20 - 67岁之间且于1980年1月1日就业的男性和女性。从1981年1月至1998年12月追踪全因死亡率。
即使在对个体1980年的失业经历进行调整后,居住地区的失业率仍与死亡率增加相关(风险比(最高四分位数与最低四分位数)1.35:0.14 - 1.60),个体1980年的失业经历也是一个风险因素(风险比(是/否)1.38:1.16 - 1.64)。当考虑其他社会和行为协变量时,这些估计值有所减弱。男性和女性的影响相似,但个体一年和五年的失业经历的影响随着年龄增长逐渐降低。
这项前瞻性研究表明,即使在对其他社会和行为因素进行调整后,当地的高失业率和个体的失业经历仍会增加死亡风险。