Rojas Bravo F, Montero L
Departamento de Cirugía General, Hospital Nacional Edgardo Rebagliati Martins, IPSS, Lima-Perú.
Rev Gastroenterol Peru. 1992;12(1):13-7.
627 cases of gastric cancer treated surgically during the last 5 years, at the Hospital Nacional "Edgardo Rebagliati Martins" from Instituto Peruano de Seguridad Social (Lima-Perú) were revised. 4 of the patients had been operated before of hemigastrectomy or antrectomy with pyloroplasty for peptic ulcer. The time between the first operation and diagnosis of cancer of the gastric stump was more than 20 years. 3 of these cases were able to be resected. The international incidence of cancer in the gastric stump is 1.1% to 9.2% according to different authors. The risk is higher after 15 years. In the pathogenesis are advocated the lower gastric acidity, biliary reflux, the presence of bacteria, the formation of nitrosamines, intestinal metaplasia, etc. Is necessary to perform periodic endoscopic survey in patients who were treated surgically of peptic ulcer with antrectomy or hemigastrectomy with more than 15 years of evolution.
对秘鲁社会保障局国立“埃德加多·雷瓦利亚蒂·马丁斯”医院(秘鲁利马)过去5年接受手术治疗的627例胃癌患者进行了回顾。其中4例患者曾因消化性溃疡接受过半胃切除术或胃窦切除术加幽门成形术。首次手术至胃残端癌诊断的时间超过20年。其中3例病例能够进行切除。根据不同作者的研究,胃残端癌的国际发病率为1.1%至9.2%。15年后风险更高。在发病机制方面,有人主张胃酸降低、胆汁反流、细菌存在、亚硝胺形成、肠化生等。对于接受过胃窦切除术或半胃切除术治疗消化性溃疡且病程超过15年的患者,有必要定期进行内镜检查。