Grunberg Gregory E, Crater Suzanne W, Green Cynthia L, Seskevich Jon, Lane James D, Koenig Harold G, Bashore Thomas M, Morris Kenneth G, Mark Daniel B, Krucoff Mitchell W
Division of Cardiology, Department of Medicine, Durham Veterans Administration Medical Center and the Duke Clinical Research Institute, Durham, North Carolina, USA.
Cardiol Rev. 2003 Nov-Dec;11(6):309-17. doi: 10.1097/01.crd.0000089947.20354.d5.
We studied the relationship between mood and mood shift immediately before percutaneous coronary intervention (PCI) and 3 end points: total ischemic burden during PCI, adverse cardiac end points (ACE) after PCI, and death by 6-month follow up. Patients (n = 119) with unstable angina or myocardial infarction completed a visual analog scale (VAS) twice before PCI; before and after a session of stress relaxation, imagery, or touch; or approximately 30 minutes apart for patients assigned to prayer or to standard care. VAS included happiness, satisfaction, calm, hope, worry, shortness of breath, fear, and sadness. We observed a significant correlation between higher hope score before PCI and lower ischemic burden. Patients who experienced ACE had significantly lower hope and happiness scores than those who did not. Patients who survived to 6 months had significantly greater increases in worry and in hope. Our data suggest correlations between simple mood assessments before PCI and clinical outcomes during and after the procedure. More study is needed to understand whether attempts to alter patient mood can affect clinical outcomes.
我们研究了经皮冠状动脉介入治疗（PCI）前即刻的情绪与情绪变化之间的关系，以及3个终点指标：PCI期间的总缺血负荷、PCI术后的不良心脏终点（ACE）和6个月随访期内的死亡情况。不稳定型心绞痛或心肌梗死患者（n = 119）在PCI前两次完成视觉模拟量表（VAS）；在进行一次压力放松、意象引导或触摸治疗之前和之后；或者对于分配到祈祷组或标准护理组的患者，两次测量间隔约30分钟。VAS包括幸福、满意度、平静、希望、担忧、呼吸急促、恐惧和悲伤。我们观察到PCI前较高的希望得分与较低的缺血负荷之间存在显著相关性。经历ACE的患者的希望和幸福得分显著低于未经历者。存活至6个月的患者的担忧和希望增加显著。我们的数据表明PCI前简单的情绪评估与手术期间及术后的临床结果之间存在相关性。需要更多研究来了解改变患者情绪的尝试是否会影响临床结果。
