Harrat Z, Belkaid M
Institut Pasteur d'Algérie, Service de parasitologie-mycologie, 2 rue du Dr Laveran, 16000 El Hamma, Alger.
Bull Soc Pathol Exot. 2003 Aug;96(3):212-4.
The authors review the situation on human and canine leishmaniasis observed in Algiers during the period 1990-1997. 1800 sera have been tested by IFAT. The frequency of canine leishmaniasis rises to 37%. 25% of the positive dogs are asymptomatic. The canine leishmaniasis annual fluctuations seem to vary from one year to another, with an increase of number of cases comparing with the last period. Human leishmaniasis is also increasing in Algiers, where 22 cases of HVL and 40 cases CL have been notified. Nine strains of Leishmania (5 from dogs and 4 from human) were isolated and identified by isoenzymes eletrophoresis technique. All stocks were belonging to Leishmania infantum complex. To complete the study, the seasonal dynamic of phlebotomine sandflies was carried out in the same area where 2959 specimens have been captured. The results showed the predominance of P. perniciosus and P. longicuspis, the main vectors of visceral leishmaniasis in Algeria.
作者回顾了1990 - 1997年期间在阿尔及尔观察到的人类和犬类利什曼病情况。已通过间接荧光抗体试验(IFAT)检测了1800份血清。犬类利什曼病的发病率升至37%。25%的阳性犬没有症状。犬类利什曼病的年度波动似乎每年都有所不同,与上一时期相比病例数有所增加。阿尔及尔的人类利什曼病也在增加,已报告22例皮肤利什曼病(HVL)和40例内脏利什曼病(CL)。通过同工酶电泳技术分离并鉴定了9株利什曼原虫(5株来自犬,4株来自人类)。所有菌株均属于婴儿利什曼原虫复合体。为完成该研究,在同一地区开展了白蛉的季节动态研究,共捕获2959只标本。结果显示,在阿尔及利亚,致病白蛉和长喙白蛉是内脏利什曼病的主要传播媒介,且占主导地位。