Epstein Arnold M, Weissman Joel S, Schneider Eric C, Gatsonis Constantine, Leape Lucian L, Piana Robert N
Division of General Medicine (Section on Health Services and Policy Research), Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
Med Care. 2003 Nov;41(11):1240-55. doi: 10.1097/01.MLR.0000093423.38746.8C.
Numerous studies have documented substantial differences by race and gender in the use of coronary artery bypass graft surgery and percutaneous coronary angioplasty. However, few studies have examined whether these differences reflect problems in quality of care.
We selected a random sample stratified by gender, race, and income of 5026 Medicare beneficiaries aged 65 to 75 who underwent inpatient coronary angiography during 1991 to 1992 in 1 of 5 states. We compared the frequency of 2 problems in quality by race and gender: underuse or the failure to receive a clinically indicated revascularization procedure and receipt of revascularization when it was not clinically indicated. We used 2 independent sets of criteria developed by the RAND Corporation and the American College of Cardiology/American Hospital Association (ACC/AHA). We also examined survival of the cohort through March 31, 1994.
Revascularization procedures were clinically indicated more frequently among whites than blacks and among men than women. Failure to receive revascularization when it was indicated was more common among blacks than among whites (40% vs. 23-24%, depending on the criteria, both P<0.001) but similar among men and women (25% vs. 22-24%, P>0.05). Racial disparities remained similar after adjusting for patient and hospital characteristics. Among patients rated inappropriate, use of procedures was greater for whites than blacks using RAND criteria (10.5% vs. 5.8%, P<0.01) and greater for men than for women (14.2% vs. 5.3% by RAND criteria, P=0.001; 8.2% vs. 4.0%% by ACC/AHA criteria, P=0.04). After multivariate adjustment, the disparities for race and gender remained similar and were statistically significant using RAND criteria. Mortality rates tended to validate our appropriateness criteria for underuse.
Racial differences in procedure use reflect higher rates of clinical appropriateness among whites, greater underuse among blacks, and more frequent revascularization when it was not clinically indicated among whites. Underuse is associated with higher mortality. In contrast, men had higher rates of clinical appropriateness and were more likely to receive revascularization when it was not clinically indicated. There was no evidence of greater underuse among women.
大量研究记录了冠状动脉搭桥手术和经皮冠状动脉腔内血管成形术在使用上存在显著的种族和性别差异。然而,很少有研究探讨这些差异是否反映了医疗质量问题。
我们从1991年至1992年期间在5个州之一接受住院冠状动脉造影的5026名年龄在65至75岁的医疗保险受益人中,按性别、种族和收入进行分层随机抽样。我们比较了种族和性别在两个质量问题上的发生频率:未充分使用或未接受临床指征的血运重建手术,以及在无临床指征时接受血运重建手术。我们使用了由兰德公司和美国心脏病学会/美国医院协会(ACC/AHA)制定的两组独立标准。我们还研究了该队列至1994年3月31日的生存率。
白人比黑人、男性比女性更频繁地有临床指征进行血运重建手术。有指征时未接受血运重建手术在黑人中比在白人中更常见(40%对23%-24%,取决于标准,两者P<0.001),但在男性和女性中相似(25%对22%-24%,P>0.05)。在对患者和医院特征进行调整后,种族差异仍然相似。在被评定为不适当的患者中,根据兰德标准,白人使用手术的比例高于黑人(10.5%对5.8%,P<0.01),男性高于女性(根据兰德标准为14.2%对5.3%,P=0.001;根据ACC/AHA标准为8.2%对4.0%,P=0.04)。经过多变量调整后,种族和性别的差异仍然相似,且根据兰德标准具有统计学意义。死亡率倾向于验证我们关于未充分使用的适宜性标准。
手术使用上的种族差异反映出白人临床适宜性更高,黑人未充分使用情况更严重,以及白人在无临床指征时更频繁地接受血运重建手术。未充分使用与更高的死亡率相关。相比之下,男性临床适宜性更高,且在无临床指征时更有可能接受血运重建手术。没有证据表明女性未充分使用情况更严重。