急性髓细胞白血病（M2）中与双侧绿色瘤相关的变异型复杂易位t(8;15;21)
Variant complex translocation t(8;15;21) in acute myeloblastic leukemia (M2) associated with bilateral chloroma.
作者信息
Sundareshan T S, Augustus M, Yasha T C, Shailaja S N, Lalitha N
机构信息
Department of Pathology, Kidwai Memorial Institute of Oncology, Bangalore, India.
出版信息
Cancer Genet Cytogenet. 1992 Nov;64(1):35-7. doi: 10.1016/0165-4608(92)90319-4.
PMID:1458447
Abstract
Complex translocation t(8;15;21)(q22;q21;q22) in a 9-year-old female with acute myeloblastic leukemia (M2) with bilateral chloroma is described. This particular variant type of translocation in M2 type is rare. The importance of variant translocation in defining the critical segment on the chromosomes responsible for phenotypic expression of the disease is emphasized.
摘要
描述了一名9岁患有急性髓性白血病（M2型）并伴有双侧绿色瘤的女性患者发生的复杂易位t(8;15;21)(q22;q21;q22)。M2型中这种特殊的易位变异类型很罕见。强调了变异易位在确定负责疾病表型表达的染色体关键区段方面的重要性。
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