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[缺氧应激对肾上腺髓质动脉的影响]

[Effect of hypoxic stress on the medullary arteries of the adrenal glands].

作者信息

Mihalj Marija, Pilija Vladimir

机构信息

Zavod za anatomiju, Medicinski fakultet, Novi Sad.

出版信息

Med Pregl. 2003 Jul-Aug;56(7-8):333-6. doi: 10.2298/mpns0308333m.

Abstract

INTRODUCTION

It is known that suprarenal glands consist of two parts: cortex and medulla. Functional properties of circulation in these two parts are still unknown. This is a very important problem, but only a few studies have dealt with it, whereas full attention should be paid to the problem in future researches.

MATERIAL AND METHODS

The experiment included 100 sexually experienced male rats which were exposed to hypoxia in testing chambers imitating conditions at 7000 m above sea level. In order to study blood vessels, we used a mixture of indian ink and 10% solution of gelatin and injected it into the left heart ventricle.

RESULTS AND DISCUSSION

The most outstanding finding pointed to existence of wide ischemic areas in the outer portion of zona fasciculata, along with simultaneous strong dilatation and increased number of medullary arteries. Therefore, a conclusion can be made that the number of opened medullary arteries in the suprarenal gland depends on functional conditions and needs of the organism. The method used to present our results showed that vascular network of the suprarenal glands changed dynamically under experimental conditions.

CONCLUSION

The obtained results point to functional accommodation of vascular network of suprarenal glands affected by stress, whereas medullary arteries are of predominantly functional character.

摘要

引言

已知肾上腺由两部分组成:皮质和髓质。这两部分循环的功能特性仍不清楚。这是一个非常重要的问题,但只有少数研究涉及,而在未来的研究中应充分关注该问题。

材料与方法

实验包括100只性成熟雄性大鼠,它们在模拟海拔7000米条件的测试箱中暴露于低氧环境。为了研究血管,我们使用了印度墨水和10%明胶溶液的混合物,并将其注入左心室。

结果与讨论

最显著的发现是束状带外侧存在广泛的缺血区域,同时髓质动脉强烈扩张且数量增加。因此,可以得出结论,肾上腺中开放的髓质动脉数量取决于机体的功能状态和需求。用于呈现我们结果的方法表明,在实验条件下肾上腺的血管网络动态变化。

结论

获得的结果表明肾上腺血管网络受应激影响具有功能适应性,而髓质动脉主要具有功能性特征。

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