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红蝮蛇毒液中磷脂酶A活性的南北区域差异。

North-south regional variation in phospholipase A activity in the venom of Crotalus ruber.

作者信息

Straight R C, Glenn J L, Wolt T B, Wolfe M C

机构信息

Venom Research Laboratory, Veterans Affairs Medical Center, Salt Lake City, UT 84148.

出版信息

Comp Biochem Physiol B. 1992 Nov;103(3):635-9. doi: 10.1016/0305-0491(92)90382-2.

DOI:10.1016/0305-0491(92)90382-2
PMID:1458838
Abstract
  1. Twenty-seven individual venoms from the rattlesnake species Crotalus ruber from different regions were comparatively analyzed by reverse-phase HPLC and analyzed for phospholipase A (PLA) content using a polarographic assay. 2. Two fractions containing PLA activity were detected by HPLC in the venoms of all the C. ruber specimens from southern Baja, Mexico, but specimens from southern California, U.S.A., were lacking corresponding fractions and were extremely low or lacking in PLA activity in their venoms. 3. The north-south regional variation in PLA content in C. ruber venom does not correlate with the north-south ranges (based on external morphology) of the subspecies C. ruber ruber and C. ruber lucasensis.
摘要
  1. 对来自不同地区的27种红菱背响尾蛇(Crotalus ruber)的毒液进行了反相高效液相色谱比较分析,并使用极谱分析法分析了磷脂酶A(PLA)的含量。2. 通过高效液相色谱法在来自墨西哥南下加利福尼亚的所有红菱背响尾蛇标本的毒液中检测到两个含有PLA活性的组分,但来自美国南加利福尼亚的标本缺乏相应的组分,其毒液中的PLA活性极低或不存在。3. 红菱背响尾蛇毒液中PLA含量的南北区域差异与亚种红菱背响尾蛇(Crotalus ruber ruber)和卢氏红菱背响尾蛇(Crotalus ruber lucasensis)的南北分布范围(基于外部形态)不相关。

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