Sukalich Sara, Guzick David
Department of Obstetrics and Gynecology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA.
Semin Reprod Med. 2003 Aug;21(3):309-15. doi: 10.1055/s-2003-43309.
Polycystic ovary syndrome (PCOS) is arguably the most common endocrinopathy among women of reproductive age. Women with PCOS have clinical characteristics that are associated with insulin resistance, vascular dysfunction, hypertension, and dyslipidemia. Although definitive data for increased cardiovascular events in women with PCOS are lacking, case-control studies have documented an increased risk of preclinical cardiovascular disease. Thus, PCOS should be viewed as a chronic condition that may ultimately have long-term health impacts and patients should be counseled to reduce cardiovascular risk factors through weight control, exercise, and/or pharmacologic treatments.
多囊卵巢综合征(PCOS)可以说是育龄女性中最常见的内分泌疾病。患有PCOS的女性具有与胰岛素抵抗、血管功能障碍、高血压和血脂异常相关的临床特征。尽管缺乏PCOS女性心血管事件增加的确切数据,但病例对照研究已记录了临床前心血管疾病风险的增加。因此,PCOS应被视为一种可能最终对长期健康产生影响的慢性疾病,并且应该建议患者通过控制体重、运动和/或药物治疗来降低心血管危险因素。