Talbott E O, Zborowskii J V, Boudraux M Y
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Minerva Ginecol. 2004 Feb;56(1):27-39.
Polycystic ovary syndrome (PCOS) is a reproductive endocrine disorder found in ~5% of the general population and is characterized by chronic anovulation, hyperandrogenism, and insulin resistance. Women with PCOS are at increased risk for the development of Type II diabetes and may represent a unique group of women at high risk for the development of coronary heart disease (CHD). More adverse CHD risk profiles of women with PCOS have been demonstrated in several studies, yet actual health outcome studies have been inconclusive as to whether this translates into increased rates of cardiovascular disease in PCOS cases when compared to controls. This review focuses on the controversy surrounding the potential relationship between cardiovascular disease outcomes and polycystic ovary syndrome.
多囊卵巢综合征（PCOS）是一种在约5%的普通人群中发现的生殖内分泌紊乱疾病，其特征为慢性无排卵、高雄激素血症和胰岛素抵抗。患有PCOS的女性患II型糖尿病的风险增加，并且可能代表了一组患冠心病（CHD）风险较高的独特女性群体。多项研究已证实PCOS女性有更多不良的CHD风险特征，但与对照组相比，关于这是否会导致PCOS患者心血管疾病发生率增加的实际健康结局研究尚无定论。本综述聚焦于围绕心血管疾病结局与多囊卵巢综合征之间潜在关系的争议。
