Kashiwagi Maki, Zimmermann Roland, Beinder Ernst
Department of Obstetrics and Gynecology, Clinic of Obstetrics, University Hospital Zurich, Frauenklinikstrasse 10, 8091 Zurich, Switzerland.
Curr Hypertens Rep. 2003 Dec;5(6):493-7. doi: 10.1007/s11906-003-0057-2.
Women with chronic hypertension and pregnancy-induced hypertension are at substantial risk for developing pre-eclampsia/eclampsia, a disease with high fetomaternal morbidity and mortality. However, the etiology of this disease is still unknown. In this article, recent concepts on the pathophysiology of pre-eclampsia, with special attention to the role of nitric oxide, are reviewed.
患有慢性高血压和妊娠期高血压的女性患先兆子痫/子痫的风险很大,这是一种母婴发病率和死亡率都很高的疾病。然而,这种疾病的病因仍然不明。本文综述了先兆子痫病理生理学的最新概念,特别关注一氧化氮的作用。