Rodrigues Adriano C T, Dalgalarrondo Paulo
Departamento de Psicologia Médica e Psiquiatria, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.
Arq Neuropsiquiatr. 2003 Sep;61(3B):876-80. doi: 10.1590/s0004-282x2003000500034. Epub 2003 Oct 28.
Wilson's disease consists in a inborn error of metabolism with marked neuropsychiatric manifestations. These manifestations need to be correctly identified and treated. There are four neuropsychiatric symptoms clusters established for Wilson's disease patients: behavior and/or personality disorders, mood disorders, cognitive deficits, and psychotic manifestations. Although such patients are more commonly seen in neurological and hepatological settings, mental health professionals must keep in mind a high level of suspicion, once first presentations may be of psychiatric nature. This study presents a review of literature about neuropsychiatric aspects of Wilson's disease, emphasizing diagnostic issues. It is presented the case of a 26 years old male patient initially with psychiatric polimorfic symptoms. The treatment of this patient with electroconvulsive therapy is presented, adding a report of this therapeutic modality, applied to that case, to the two only previous records in the literature.
威尔逊氏病是一种伴有明显神经精神症状的先天性代谢紊乱疾病。这些症状需要得到正确识别和治疗。针对威尔逊氏病患者确定了四个神经精神症状群:行为和/或人格障碍、情绪障碍、认知缺陷以及精神病性表现。尽管这类患者在神经科和肝病科环境中更为常见,但心理健康专业人员必须保持高度怀疑,因为首次表现可能具有精神科性质。本研究对有关威尔逊氏病神经精神方面的文献进行了综述,重点强调诊断问题。报告了一名26岁男性患者的病例,该患者最初有多种精神症状。介绍了对该患者进行电休克治疗的情况,并将该治疗方式应用于该病例的报告补充到文献中仅有的另外两篇记录中。