Tahery D P, Moy R L
UCLA Division of Dermatology, Veterans Administration Wadsworth West Los Angeles Medical Center, California.
Int J Dermatol. 1992 Sep;31(9):629-31. doi: 10.1111/j.1365-4362.1992.tb03980.x.
Through the UCLA tumor registry, patients treated for late-relapse malignant melanoma (after a 10-year disease-free interval) were identified and studied retrospectively. The patients were studied in regards to age, sex, primary site of the lesion, the disease-free interval, elective lymph node dissection, mode of recurrence and survival time following relapse. The histologic characteristics studied included the maximal tumor thickness, Clark's levels, rate of mitoses, and presence of ulceration. Based on the 0.84% incidence of late-relapse, the recommendation for annual life-time follow-up examinations for all patients with malignant melanoma is supported.
通过加州大学洛杉矶分校肿瘤登记处，对晚期复发恶性黑色素瘤患者（无病间隔10年后）进行了识别并进行回顾性研究。对患者的年龄、性别、病变原发部位、无病间隔、选择性淋巴结清扫、复发模式以及复发后的生存时间进行了研究。所研究的组织学特征包括肿瘤最大厚度、克拉克分级、有丝分裂率以及溃疡情况。基于0.84%的晚期复发率，支持对所有恶性黑色素瘤患者进行终身年度随访检查的建议。
