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线粒体生物能量学、衰老及衰老相关疾病。

Mitochondrial bioenergetics, aging, and aging-related disease.

作者信息

Nicholls David

机构信息

Buck Institute for Age Research, Novato, CA 94945, USA.

出版信息

Sci Aging Knowledge Environ. 2002 Aug 7;2002(31):pe12. doi: 10.1126/sageke.2002.31.pe12.

DOI:10.1126/sageke.2002.31.pe12
PMID:14603000
Abstract

In this Perspective, the author discusses some of the bioenergetic consequences of the various alterations in mitochondrial function that have been hypothesized to be associated with human aging and aging-related disease. Special focus is afforded to neurodegenerative disease.

摘要

在这篇综述中，作者讨论了线粒体功能的各种改变所带来的一些生物能量学后果，这些改变被认为与人类衰老及衰老相关疾病有关。特别关注的是神经退行性疾病。

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