Ito Hiroyuki, Nakayama H, Arai H, Karita S, Shotsu A, Fujita A
Division of General Thoracic Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Kyobu Geka. 2003 Nov;56(12):1014-6.
We investigated the comparative effectiveness of the seat and glue types of fibrin adhesive, to clarify which is more useful in preventing postoperative parenchymal air leaks after lung resection. One hundred sixteen patients received fibrin adhesive to prevent postoperative air leakage after lung resection carried out by the same surgeon. Ninety-two lobectomies and 24 partial resections were assessed. There were 29 patients with emphysematous lung. In the seat type group, an average of 2.6 postoperative days elapsed before chest drain removal. In the glue type, this average was 3.2 days, a significant difference. This difference was also evident in the lobectomy group. However, among emphysematous lung patients and the partial resection group, there was no apparent difference. Prolonged air leakage was seen in 2 patients with emphysematous lung, but no difference in terms of drug formation could be seen. The seated type of fibrin adhesive was more useful than the glue type in preventing postoperative air leaks, but in emphysematous lung patients, better surgical technique would seem to be the critical factor.
我们研究了座式和胶式纤维蛋白粘合剂的相对有效性，以明确哪种在预防肺切除术后实质性漏气方面更有用。116例患者在同一位外科医生进行肺切除术后接受了纤维蛋白粘合剂以预防漏气。评估了92例肺叶切除术和24例部分切除术。有29例肺气肿患者。在座式组中，平均术后2.6天拔除胸腔引流管。在胶式组中，这一平均值为3.2天，差异显著。这种差异在肺叶切除术组中也很明显。然而，在肺气肿患者和部分切除术组中，没有明显差异。2例肺气肿患者出现了持续性漏气，但在药物形成方面没有差异。座式纤维蛋白粘合剂在预防术后漏气方面比胶式更有用，但对于肺气肿患者，更好的手术技术似乎是关键因素。
