横向去相位优化固态核磁共振光谱学。

Transverse dephasing optimized solid-state NMR spectroscopy.

作者信息

De Paëpe G, Giraud N, Lesage A, Hodgkinson P, Böckmann A, Emsley L

机构信息

Laboratoire de Chimie, UMR 5182 CNRS/ENS, Laboratoire de Recherche Conventionné du CEA (no. 23V), Ecole Normale Supérieure de Lyon, 69364 Lyon, France.

出版信息

J Am Chem Soc. 2003 Nov 19;125(46):13938-9. doi: 10.1021/ja037213j.

DOI:10.1021/ja037213j

PMID:14611212

Abstract

It is shown how coherence lifetimes in solid-state NMR experiments can be controlled. New decoupling schemes are introduced which actively optimize dephasing times, providing increases of up to a factor of 2 with respect to the best existing schemes. The new schemes are implemented in transverse-dephasing-optimized (TDOP) NMR experiments for the disorded solid cellulose, and for a microcrystalline protein, where sensitivity improvements of up to a factor of 5 are obtained.

摘要

展示了如何在固态核磁共振实验中控制相干寿命。引入了新的去耦方案，这些方案能主动优化退相时间，相较于现有的最佳方案，可将退相时间提高多达两倍。新方案在横向退相优化（TDOP）核磁共振实验中得以实现，用于无序固体纤维素以及一种微晶蛋白，在这些实验中灵敏度提高了多达五倍。