Badran Rohini, Rk Daniel, Singhal Vinay, Bhatnagar Dinesh
Department of Cancer and General Surgery, Vardhman Mahavir Medical College, Safdarjang Hospital, New Delhi, 110023, India.
World J Surg Oncol. 2003 Nov 3;1(1):23. doi: 10.1186/1477-7819-1-23.
Radiotherapy in the radical doses can produce severe and often irreversible damage to the gut in the form of fibrosis, necrosis and fistulae formation. A previous pelvic surgery makes the gut extra-vulnerable. This is on account of adhesions to the pelvic wall, unless special care is taken during surgery to keep it out of the harms way, during adjuvant radiotherapy. These effects range from acute, to sub acute and delayed chronic manifestations like in the reported case. CASE REPORT: A spontaneous low out put enterocutaneous fistula in a 68-year-old man following surgery and adjuvant radiotherapy given 27 years back for carcinoma penis is reported. Patient is making a satisfactory progress after three years of follow-up. CONCLUSION: High dose external beam radiotherapy is known to produce deleterious side effects ranging from mild radiation enteritis to the development of internal and external fistulae. The effects may be acute, subacute or chronic. Presentation as spontaneous enterocutaneous fistula 27 years after radiotherapy is rare.
根治性剂量的放疗会对肠道造成严重且往往不可逆的损伤,表现为纤维化、坏死和瘘管形成。既往盆腔手术会使肠道格外脆弱。这是由于与盆腔壁粘连,除非在辅助放疗期间手术时特别小心以使其免受伤害。这些影响范围从急性到亚急性,再到延迟的慢性表现,如本报告病例所示。病例报告:报告了一名68岁男性在27年前因阴茎癌接受手术和辅助放疗后出现自发性低位肠皮肤瘘。经过三年随访,患者恢复情况良好。结论:已知高剂量外照射放疗会产生有害副作用,从轻度放射性肠炎到内外瘘的形成。这些影响可能是急性、亚急性或慢性的。放疗27年后出现自发性肠皮肤瘘的情况罕见。