Gandelman-Marton R, Kimiagar I, Itzhaki A, Klein C, Theitler J, Rabey J M
Department of Neurology, Assaf-Harofeh Medical Center, Zerifin, Israel.
Clin Infect Dis. 2003 Dec 1;37(11):1573-8. doi: 10.1086/379516. Epub 2003 Oct 14.
Eighteen adult patients with serologically confirmed West Nile virus (WNV)-associated meningitis or meningoencephalitis were admitted to our hospital during the 2000 West Nile fever outbreak in Israel. Thirteen of the patients had a more severe and prolonged clinical course, and an electroencephalogram (EEG) was, therefore, requested. A specific EEG pattern was seen in 8 patients, consisting of generalized slowing, which was more prominent over the anterior regions. Generalized slowing that was prominent over the temporal area was seen in 2 patients, and intermittent slowing over the temporal region was seen in 1 patient. Two patients had normal EEG findings. We suggest that WNV meningoencephalitis should be considered in the differential diagnosis of meningitis or meningoencephalitis with a prolonged clinical course and anteriorly predominant slowing on an EEG.
在2000年以色列西尼罗河热疫情爆发期间，18名血清学确诊为西尼罗河病毒（WNV）相关脑膜炎或脑膜脑炎的成年患者被收治入我院。其中13名患者临床病程更为严重且持续时间更长，因此进行了脑电图（EEG）检查。8名患者出现了特定的脑电图模式，表现为广泛性减慢，在前部区域更为明显。2名患者在颞区出现明显的广泛性减慢，1名患者在颞区出现间歇性减慢。2名患者脑电图结果正常。我们建议，对于临床病程较长且脑电图显示前部为主的减慢的脑膜炎或脑膜脑炎，在鉴别诊断时应考虑WNV脑膜脑炎。
