Coyne K S, Wiklund I, Schmier J, Halling K, Degl' Innocenti A, Revicki D
MEDTAP International, Bethesda, MD 20814, USA.
Aliment Pharmacol Ther. 2003 Nov 1;18(9):907-15. doi: 10.1046/j.1365-2036.2003.01674.x.
Currently, no disease-specific, patient-based, treatment satisfaction instruments related to gastro-oesophageal reflux disease exist.
To develop and validate a treatment satisfaction questionnaire for gastro-oesophageal reflux disease (TSQ-G).
A new questionnaire was developed from patient focus groups, clinician input and literature review. A validation study was conducted in treated gastro-oesophageal reflux disease patients. Ancillary measures included the Medical Outcomes Study Short Form-36, Quality of Life in Reflux and Dyspepsia, Gastrointestinal Symptom Rating Scale, Socially Desirable Response Scale, Patient Satisfaction Questionnaire-18 and physician and patient measures of symptoms and satisfaction. Statistical analyses included exploratory factor analysis, Cronbach's alpha, intra-class correlations, analyses of variance and t-tests.
A total of 198 gastro-oesophageal reflux disease patients participated in the study, with a mean age of 50.7 years, 68% female and 84% Caucasian. The physician-rated severity of gastro-oesophageal reflux disease was mild (32%), moderate (50%) and severe (18%); 83% were on proton pump inhibitors. The final TSQ-G consisted of 28 items with seven sub-scales; Cronbach's alpha ranged from 0.58 to 0.94. Correlations with the expected sub-scales of the ancillary measures were moderate to strong. The TSQ-G sub-scales discriminated significantly between levels of physician-rated disease severity, symptom days and patient and physician ratings of satisfaction.
The TSQ-G has excellent reliability and construct validity and appears to be a useful tool for the evaluation of treatment satisfaction in gastro-oesophageal reflux disease patients.
目前，尚无针对胃食管反流病的、基于患者的疾病特异性治疗满意度评估工具。
开发并验证胃食管反流病治疗满意度问卷（TSQ-G）。
通过患者焦点小组、临床医生意见及文献综述开发了一份新问卷。对接受治疗的胃食管反流病患者进行了验证研究。辅助测量包括医学结局研究简表-36、反流和消化不良生活质量、胃肠道症状评定量表、社会期望反应量表、患者满意度问卷-18以及医生和患者对症状及满意度的测量。统计分析包括探索性因子分析、克朗巴赫α系数、组内相关系数、方差分析和t检验。
共有198例胃食管反流病患者参与研究，平均年龄50.7岁，68%为女性，84%为白种人。医生评定的胃食管反流病严重程度为轻度（32%）、中度（50%）和重度（18%）；83%的患者正在使用质子泵抑制剂。最终的TSQ-G由28个项目和7个分量表组成；克朗巴赫α系数范围为0.58至0.94。与辅助测量预期分量表的相关性为中度至高度。TSQ-G分量表在医生评定的疾病严重程度、症状天数以及患者和医生的满意度评分水平之间有显著差异。
TSQ-G具有出色的信度和结构效度，似乎是评估胃食管反流病患者治疗满意度的有用工具。
