Emanuelson I, Andersson Holmkvist E, Björklund R, Stålhammar D
Department for Health of Women and Children, Göteborg University, Göteborg, Sweden.
Acta Neurol Scand. 2003 Nov;108(5):332-8. doi: 10.1034/j.1600-0404.2003.00155.x.
To study quality of life and subjective post-concussion symptoms in adults (16-60 years) with a mild traumatic brain injury (MTBI) 3 months and 1 year after injury.
Of a total of 489 patients 173 responded to questionnaires at 3 months and at 1 year, including the SF-36 health-related quality of life survey, which is a standardized measure validated for Swedish conditions. Post-concussion symptoms were rated as either existing or non-existing in a 21-item checklist [a modified version of Comprehensive Psychopathological Rating Scale (CPRS)].
SF-36 showed impaired scores in all dimensions. Existing post-concussion symptoms were reported by 1545%. Significantly, more symptoms were present at 3 months than at 3 weeks after injury. Furthermore, a significant correlation between higher rates of post-concussion symptoms and lower SF-36 scores was found.
The SF-36 results were significantly impaired compared with an age- and gender-matched normative control group and the rate of post-concussion symptoms was significantly higher at 3 months than at 3 weeks after injury. As a significant correlation between higher rates of symptoms and low SF-36 scores was also found we assume SF-36 to be a sensitive enough measure of MTBI-related effects.
研究轻度创伤性脑损伤(MTBI)成年患者(16 - 60岁)在受伤后3个月和1年时的生活质量及主观脑震荡后症状。
在总共489名患者中,173名患者在3个月和1年时回复了问卷,包括SF - 36健康相关生活质量调查,这是一项针对瑞典情况验证过的标准化测量方法。脑震荡后症状通过一份21项清单(综合精神病理学评定量表(CPRS)的修订版)评定为存在或不存在。
SF - 36在所有维度上得分均受损。报告存在脑震荡后症状的比例为1545%。显著的是,受伤后3个月出现的症状比3周时更多。此外,发现脑震荡后症状发生率较高与SF - 36得分较低之间存在显著相关性。
与年龄和性别匹配的正常对照组相比,SF - 36结果显著受损,且受伤后3个月脑震荡后症状发生率显著高于3周时。由于还发现症状发生率较高与SF - 36低分之间存在显著相关性,我们认为SF - 36是MTBI相关影响的足够敏感的测量方法。