García Leoni M E, Esclarín De Ruz A
Infectious Disease Unit, Department of Internal Medicine, Hospital Nacional de Parapléjicos, Toledo, Spain.
Clin Microbiol Infect. 2003 Aug;9(8):780-5. doi: 10.1046/j.1469-0691.2003.00643.x.
Urinary tract infection (UTI) is responsible for major morbidity and mortality in spinal cord injury (SCI) patients. Several factors appear to be responsible for an increased risk of infection in the neurogenic bladder. Incomplete voiding, elevated intravesical pressure and catheter use contribute to an increased risk of symptomatic urinary tract infection. Frequent exposure to antibiotics increases the risk of infection by resistant organisms. UTIs interfere with rehabilitation, and may lead to secondary urologic complications. The classic symptoms of UTI are unreliable indicators in SCI patients with neurogenic bladder. Lack of pyuria reasonably predicts the absence of UTI in SCI patients. Asymptomatic bacteriuria need not be treated with antibiotics. Symptomatic UTI warrants therapy in all patients.
尿路感染（UTI）是脊髓损伤（SCI）患者发病和死亡的主要原因。神经源性膀胱感染风险增加似乎有几个因素。排尿不完全、膀胱内压升高和使用导尿管会增加有症状尿路感染的风险。频繁接触抗生素会增加耐药菌感染的风险。尿路感染会干扰康复，并可能导致继发性泌尿系统并发症。UTI的典型症状在患有神经源性膀胱的SCI患者中不是可靠的指标。无脓尿合理地预示着SCI患者没有UTI。无症状菌尿无需用抗生素治疗。有症状的UTI在所有患者中都需要治疗。
