Ioannidou E, Padilla J, Wang J, Heymsfield S B, Thornton J C, Horlick M, Gallagher D, Pierson R N
New York Obesity Research Center St Luke's-Roosevelt Hospital, Institute of Human Nutrition College of Physicians and Surgeons, Columbia University, New York, USA.
Acta Diabetol. 2003 Oct;40 Suppl 1:S83-5. doi: 10.1007/s00592-003-0034-x.
Dual-energy X-ray absorptiometry (DXA) provides an important opportunity for estimating total body skeletal muscle (SM) mass from DXA-measured appendicular lean soft tissue (ALST). A DXA SM prediction model was developed with magnetic resonance imaging as the reference and ALST (i. e., sum of arm plus leg lean soft tissue) as a main predictor variable. In the present study we examined whether ALST estimates are comparable across systems (i. e., penciland fan-beam) and manufacturers. Pencil-beam systems (Lunar DPX and DPX-L) are usually considered more accurate but slower than fan-beam systems (Lunar Prodigy and Hologic Delphi A). In this study we compared ALST estimates in 35 healthy adults across these four systems. The methods gave similar group mean (+/-SD) values and were highly intercorrelated. There was no significant bias detected across the four systems. ALST estimates from the evaluated DXA systems are comparable and thus appear interchangeable as methods for quantifying total body SM in vivo.
双能X线吸收法（DXA）为从DXA测量的四肢瘦软组织（ALST）估计全身骨骼肌（SM）质量提供了重要机会。以磁共振成像为参考，以ALST（即手臂加腿部瘦软组织之和）作为主要预测变量，开发了一种DXA SM预测模型。在本研究中，我们检查了不同系统（即笔形束和扇形束）和制造商之间的ALST估计值是否具有可比性。笔形束系统（Lunar DPX和DPX-L）通常被认为比扇形束系统（Lunar Prodigy和Hologic Delphi A）更准确，但速度较慢。在本研究中，我们比较了这四个系统中35名健康成年人的ALST估计值。这些方法给出了相似的组均值（±标准差），并且高度相关。在这四个系统中未检测到显著偏差。所评估的DXA系统的ALST估计值具有可比性，因此作为体内量化全身SM的方法似乎可以互换。
