• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

人工心脏瓣膜内血流的数值模拟:网格分辨率与血流对称性假设

Numerical simulation of flow in mechanical heart valves: grid resolution and the assumption of flow symmetry.

作者信息

Ge Liang, Jones S Casey, Sotiropoulos Fotis, Healy Timothy M, Yoganathan Ajit P

机构信息

School of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta, GA 30332-0335, USA.

出版信息

J Biomech Eng. 2003 Oct;125(5):709-18. doi: 10.1115/1.1614817.

DOI:10.1115/1.1614817
PMID:14618930
Abstract

A numerical method is developed for simulating unsteady, 3-D, laminar flow through a bileaflet mechanical heart valve with the leaflets fixed. The method employs a dual-time-stepping artificial-compressibility approach together with overset (Chimera) grids and is second-order accurate in space and time. Calculations are carried out for the full 3-D valve geometry under steady inflow conditions on meshes with a total number of nodes ranging from 4 x 10(5) to 1.6 x 10(6). The computed results show that downstream of the leaflets the flow is dominated by two pairs of counter-rotating vortices, which originate on either side of the central orifice in the aortic sinus and rotate such that the common flow of each pair is directed away from the aortic wall. These vortices intensify with Reynolds number, and at a Reynolds number of approximately 1200 their complex interaction leads to the onset of unsteady flow and the break of symmetry with respect to both geometric planes of symmetry. Our results show the highly 3-D structure of the flow; question the validity of computationally expedient assumptions of flow symmetry; and demonstrate the need for highly resolved, fully 3-D simulations if computational fluid dynamics is to accurately predict the flow in prosthetic mechanical heart valves.

摘要

开发了一种数值方法,用于模拟通过固定瓣叶的双叶机械心脏瓣膜的非定常三维层流。该方法采用双时间步长人工可压缩性方法以及重叠(嵌套)网格,在空间和时间上具有二阶精度。在稳定流入条件下,对具有4×10⁵至1.6×10⁶个节点总数的网格上的完整三维瓣膜几何形状进行了计算。计算结果表明,在瓣叶下游,流动由两对反向旋转的涡旋主导,这些涡旋起源于主动脉窦中央孔的两侧,并以这样的方式旋转,使得每对涡旋的共同流动方向远离主动脉壁。这些涡旋随着雷诺数的增加而增强,在雷诺数约为1200时,它们的复杂相互作用导致非定常流动的开始以及相对于两个几何对称平面的对称性破坏。我们的结果显示了流动的高度三维结构;质疑了计算上方便的流动对称性假设的有效性;并证明,如果计算流体动力学要准确预测人工机械心脏瓣膜中的流动,则需要进行高分辨率的全三维模拟。

相似文献

1
Numerical simulation of flow in mechanical heart valves: grid resolution and the assumption of flow symmetry.人工心脏瓣膜内血流的数值模拟:网格分辨率与血流对称性假设
J Biomech Eng. 2003 Oct;125(5):709-18. doi: 10.1115/1.1614817.
2
Flow in a mechanical bileaflet heart valve at laminar and near-peak systole flow rates: CFD simulations and experiments.在层流和接近峰值收缩期流速下机械双叶心脏瓣膜中的流动:计算流体动力学模拟与实验
J Biomech Eng. 2005 Oct;127(5):782-97. doi: 10.1115/1.1993665.
3
Validation of a fluid-structure interaction model of a heart valve using the dynamic mesh method in fluent.使用Fluent中的动态网格法对心脏瓣膜的流固耦合模型进行验证。
Comput Methods Biomech Biomed Engin. 2004 Jun;7(3):139-46. doi: 10.1080/10255840410001715222.
4
A novel computational model for the hemodynamics of bileaflet mechanical valves in the opening phase.一种用于双叶机械瓣膜开启阶段血流动力学的新型计算模型。
Proc Inst Mech Eng H. 2015 Mar;229(3):232-44. doi: 10.1177/0954411915576944.
5
A three-dimensional, time-dependent analysis of flow through a bileaflet mechanical heart valve: comparison of experimental and numerical results.双叶机械心脏瓣膜内血流的三维时变分析:实验与数值结果比较
J Biomech. 1996 May;29(5):609-18. doi: 10.1016/0021-9290(95)00107-7.
6
Numerical simulation of unsteady laminar flow through a tilting disk heart valve: prediction of vortex shedding.倾斜盘式心脏瓣膜非定常层流的数值模拟:涡旋脱落的预测。
J Biomech. 1994 Apr;27(4):391-402. doi: 10.1016/0021-9290(94)90015-9.
7
Characterization of hemodynamic forces induced by mechanical heart valves: Reynolds vs. viscous stresses.机械心脏瓣膜诱导的血流动力学力的表征:雷诺应力与粘性应力
Ann Biomed Eng. 2008 Feb;36(2):276-97. doi: 10.1007/s10439-007-9411-x. Epub 2007 Nov 30.
8
Three-dimensional study of the effect of two leaflet opening angles on the time-dependent flow through a bileaflet mechanical heart valve.双叶机械心脏瓣膜上两个瓣叶开放角度对随时间变化的血流影响的三维研究。
Med Eng Phys. 1997 Apr;19(3):235-41. doi: 10.1016/s1350-4533(96)00066-5.
9
Computational fluid dynamics study of a protruded-hinge bileaflet mechanical heart valve.一种突出铰链双叶机械心脏瓣膜的计算流体动力学研究
J Heart Valve Dis. 2001 Mar;10(2):254-262; discussion 263.
10
Particle image velocimetry for flow analysis in longitudinal planes across a mechanical artificial heart valve.用于跨机械人工心脏瓣膜纵向平面血流分析的粒子图像测速技术
Artif Organs. 2004 May;28(5):507-13. doi: 10.1111/j.1525-1594.2004.07271.x.

引用本文的文献

1
Vortex Dynamics in the Sinus of Valsalva.主动脉瓣窦内的涡旋动力学
Bioengineering (Basel). 2025 Mar 11;12(3):279. doi: 10.3390/bioengineering12030279.
2
Rethinking mechanical heart valves in the aortic position: new paradigms in design and testing.重新审视主动脉位置的机械心脏瓣膜:设计与测试的新范式
Front Cardiovasc Med. 2025 Jan 30;11:1458809. doi: 10.3389/fcvm.2024.1458809. eCollection 2024.
3
Fluid-structure interaction modeling of compliant aortic valves using the lattice Boltzmann CFD and FEM methods.使用格子玻尔兹曼计算流体力学(CFD)和有限元法(FEM)对柔顺性主动脉瓣进行流固耦合建模。
Biomech Model Mechanobiol. 2023 Jun;22(3):837-850. doi: 10.1007/s10237-022-01684-0. Epub 2023 Feb 10.
4
Clinical Impact of Computational Heart Valve Models.计算心脏瓣膜模型的临床影响
Materials (Basel). 2022 May 5;15(9):3302. doi: 10.3390/ma15093302.
5
Simulation of Mechanical Heart Valve Dysfunction and the Non-Newtonian Blood Model Approach.机械心脏瓣膜功能障碍的模拟及非牛顿血液模型方法
Appl Bionics Biomech. 2022 Apr 19;2022:9612296. doi: 10.1155/2022/9612296. eCollection 2022.
6
Computational Fluid Dynamics Assessment Associated with Transcatheter Heart Valve Prostheses: A Position Paper of the ISO Working Group.经导管心脏瓣膜假体相关的计算流体动力学评估:ISO工作组立场文件
Cardiovasc Eng Technol. 2018 Sep;9(3):289-299. doi: 10.1007/s13239-018-0349-y. Epub 2018 Apr 19.
7
Review of numerical methods for simulation of mechanical heart valves and the potential for blood clotting.机械心脏瓣膜模拟的数值方法综述及血栓形成的可能性。
Med Biol Eng Comput. 2017 Sep;55(9):1519-1548. doi: 10.1007/s11517-017-1688-9. Epub 2017 Jul 26.
8
Numerical Modeling of Intraventricular Flow during Diastole after Implantation of BMHV.植入BMHV后舒张期脑室内血流的数值模拟
PLoS One. 2015 May 11;10(5):e0126315. doi: 10.1371/journal.pone.0126315. eCollection 2015.
9
Blood damage through a bileaflet mechanical heart valve: a quantitative computational study using a multiscale suspension flow solver.双叶机械心脏瓣膜造成的血液损伤:一项使用多尺度悬浮流求解器的定量计算研究。
J Biomech Eng. 2014 Oct;136(10):101009. doi: 10.1115/1.4028105.
10
Modified control grid interpolation for the volumetric reconstruction of fluid flows.用于流体流动体积重建的改进控制网格插值法。
Exp Fluids. 2008 Dec;45(6):987-997. doi: 10.1007/s00348-008-0517-1.