Yaqoob N, Ahmad Z, Muzaffar S, Gill M S, Soomro I N, Hasan S H
Department of Pathology, Faculty of Health Sciences, Medical College, The Aga Khan University Hospital, Karachi.
J Pak Med Assoc. 2003 Sep;53(9):427-31.
To determine the frequency of various types of cutaneous appendage tumors in our practice.
This is a partly retrospective and partly prospective study conducted at the Department of Pathology, Histopathology Section, The Aga Khan University Hospital, Karachi between 1st January 1997 and 31st December 2001.
One hundred sixty six skin appendage tumors were diagnosed during the study period. 87.3% were benign, while 12.6% were malignant. Male female ratio was almost equal. Mean age was 41.72 years. 37.34% showed eccrine differentiation, 14.45% showed apocrine differentiation and 41.56% showed pilosebaceous differentiation, 6.62% exhibited mixed differentiation. The 5 commonest tumors were pilomatricoma, nodular hidradenoma (eccrine acrospiroma), syringocystadenoma papilleferum, eccrine poroma and eccrine spiradenoma. The commonest malignant tumors were porocarcinoma and sebaceous carcinoma. Pilomatricoma were common in children.
Most of our findings roughly correlate with the western published data. However, commonest site for eccrine poromas in our study was head and neck. Also, not a single case of eccrine spiradenoma was seen in the first two decades of life. These findings differ significantly from western data.
确定我们实际工作中各类皮肤附属器肿瘤的发生率。
这是一项于1997年1月1日至2001年12月31日在卡拉奇阿迦汗大学医院病理科组织病理学组进行的部分回顾性和部分前瞻性研究。
研究期间共诊断出166例皮肤附属器肿瘤。87.3%为良性，12.6%为恶性。男女比例几乎相等。平均年龄为41.72岁。37.34%显示小汗腺分化，14.45%显示大汗腺分化，41.56%显示毛囊皮脂腺分化，6.62%表现为混合分化。最常见的5种肿瘤为毛母质瘤、结节状汗腺瘤（小汗腺末端汗腺瘤）、乳头状汗管囊腺瘤、小汗腺汗孔瘤和小汗腺螺旋腺瘤。最常见的恶性肿瘤为汗孔癌和皮脂腺癌。毛母质瘤在儿童中常见。
我们的大多数发现与西方已发表的数据大致相符。然而，在我们的研究中，小汗腺汗孔瘤最常见的部位是头颈部。此外，在生命的前二十年中未见到一例小汗腺螺旋腺瘤。这些发现与西方数据有显著差异。
