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皮肤附属器肿瘤的临床病理研究

A clinicopathologic study of skin appendageal tumors.

作者信息

Nair Pradeep S

机构信息

Department of Dermatology and Venereology, Medical College Hospital, Trivandrum- 695 011, Kerala, India.

出版信息

Indian J Dermatol Venereol Leprol. 2008 Sep-Oct;74(5):550. doi: 10.4103/0378-6323.44339.

DOI:10.4103/0378-6323.44339
PMID:19086136
Abstract

BACKGROUND

Appendageal skin tumors belong to a heterogenous group of tumors with specific histopathology. The aim of this study is to determine the pattern of appendageal tumors in skin biopsies done in our department.

METHODS

This is a 3-year retrospective descriptive study of all patients who were diagnosed to have skin appendageal tumors in our department, and the diagnoses were confirmed by histopathology. The tumors were classified as eccrine, hair, sebaceous, and apocrine after a detailed examination of routine hematoxylin and eosin sections.

RESULTS

The total number of cases in the study was 33-10 males and 23 females. Tumors with eccrine differentiation constituted the maximum, 17 cases (51.5%); followed by tumors with hair differentiation, 12 cases (36.36%); tumors with sebaceous differentiation, 2 cases (6.06%); and apocrine tumors, 2 cases (6.06%). Syringoma constituted the commonest eccrine tumor, 14 cases (42.42%); while trichoepithelioma was the commonest hair tumor, 9 cases (27.27%). The other eccrine tumors were eccrine spiradenoma, 2 cases (6.06%); and nodular hidradenoma, 1 (3.03%). The other hair tumors were pilar cyst, 2 (6.06%); and pilomatricoma, 1 (3.03%). The sebaceous tumors constituted 2 cases (6.06%) of nevus sebaceous. Syringocystadenoma papilliferum, 1 (3.03%); and cylindroma, 1 (3.03%), constituted the apocrine tumors.

CONCLUSIONS

Appendageal skin tumors are relatively uncommon. Histopathology is mandatory for the diagnosis. No tumor showed malignant change in this study.

摘要

背景

附属器皮肤肿瘤属于一组具有特定组织病理学特征的异质性肿瘤。本研究的目的是确定在我科进行的皮肤活检中附属器肿瘤的模式。

方法

这是一项为期3年的回顾性描述性研究,研究对象为所有在我科被诊断为附属器皮肤肿瘤的患者,诊断经组织病理学证实。在对常规苏木精和伊红切片进行详细检查后,将肿瘤分为小汗腺、毛发、皮脂腺和大汗腺肿瘤。

结果

本研究病例总数为33例,其中男性10例,女性23例。小汗腺分化的肿瘤最多,为17例(51.5%);其次是毛发分化的肿瘤,为12例(36.36%);皮脂腺分化的肿瘤2例(6.06%);大汗腺肿瘤2例(6.06%)。汗管瘤是最常见的小汗腺肿瘤,为14例(42.42%);而毛发上皮瘤是最常见的毛发肿瘤,为9例(27.27%)。其他小汗腺肿瘤为小汗腺螺旋腺瘤2例(6.06%);结节状汗腺瘤1例(3.03%)。其他毛发肿瘤为毛囊肿2例(6.06%);毛母质瘤1例(3.03%)。皮脂腺肿瘤为皮脂腺痣2例(6.06%)。乳头状汗管囊腺瘤1例(3.03%);圆柱瘤1例(3.03%),为大汗腺肿瘤。

结论

附属器皮肤肿瘤相对少见。组织病理学检查对诊断至关重要。本研究中未发现肿瘤发生恶变。

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