Dop M C, Blot I, Dyck J L, Assimadi K, Hodonou A K, Doh A
ORSTOM Unité de Recherches Maladies de la Dénutrition, Lome, Togo.
Rev Epidemiol Sante Publique. 1992;40(4):259-67.
A prevalence study was carried out on 125 mothers and their newborns in Lome (Togo): at delivery 48% of the mothers and 30% of the newborns were anaemic according to WHO criteria. Iron deficiency was the major determinant of anaemia in the mothers, as three out of four showed at least one biochemical indicator of iron deficiency. Folate deficiency was detected in 68% of the mothers but did not influence their haematological parameters. Severe iron deficiency in the mothers (serum iron < 7 mumol/l) was associated with a decrease in serum iron in the newborns, thus demonstrating an impaired iron transfer to the fetus. Folate supplementation of the mothers during pregnancy improved their newborn's folate status. A systematic ferro-folic supplementation is needed during pregnancy and would be beneficial to both mothers and newborns. Supplements could be given to women at prenatal care clinics. Attendance in these centers by 98% of pregnant women in Lomé allows us to anticipate a good coverage for such an intervention.
在多哥洛美对125名母亲及其新生儿进行了一项患病率研究：根据世界卫生组织标准，分娩时48%的母亲和30%的新生儿贫血。缺铁是母亲贫血的主要决定因素，因为四分之三的母亲至少有一项缺铁的生化指标。68%的母亲检测出叶酸缺乏，但这并未影响她们的血液学参数。母亲严重缺铁（血清铁<7微摩尔/升）与新生儿血清铁降低有关，从而表明铁向胎儿的转运受损。孕期母亲补充叶酸可改善新生儿的叶酸状况。孕期需要进行系统性的铁叶酸补充，这对母亲和新生儿都有益。可在产前保健诊所向妇女提供补充剂。洛美98%的孕妇到这些中心就诊，这使我们预计这种干预措施能有良好的覆盖率。
