Abdelrahim Ishraga I, Adam Gamal K, Mohmmed Ahmed A, Salih Magdi M, Ali Naji I, Elbashier Mustafa I, Adam Ishag
Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
Trans R Soc Trop Med Hyg. 2009 May;103(5):493-6. doi: 10.1016/j.trstmh.2008.10.007. Epub 2008 Nov 21.
A cross-sectional study was carried out between October 2007 and January 2008 to investigate the prevalence and types of anaemia among pregnant women of eastern Sudan. Socio-demographic and obstetrical data were collected using a questionnaire. Haemoglobin (Hb), serum ferritin, serum folate and vitamin B(12) were assessed using standard laboratory methods. Two hundred and seventy-nine pregnant Sudanese women were recruited. Anaemia (Hb <11 gdl) and iron deficiency (ferritin <15 microg/l) were prevalent in 80.3 and 14.3% of the study sample, respectively. Of the total sample, 11.1% had iron-deficiency anaemia. Serum folate (<6.6 ng/ml) and vitamin B(12) (<150 pg/ml) deficiency was reported in 57.7 and 1%, respectively, and none of the women had both folate and vitamin B(12) deficiencies. Univariate and multivariate analyses showed that ferritin, serum folate and vitamin B(12) levels were not significantly associated with anaemia. Thus, there was a high prevalence of anaemia and folate deficiency. Measures to control these should be considered.
2007年10月至2008年1月期间开展了一项横断面研究,以调查苏丹东部孕妇贫血的患病率及类型。通过问卷调查收集社会人口统计学和产科数据。采用标准实验室方法评估血红蛋白(Hb)、血清铁蛋白、血清叶酸和维生素B12。招募了279名苏丹孕妇。贫血(Hb<11 g/dl)和缺铁(铁蛋白<15 μg/l)在研究样本中的患病率分别为80.3%和14.3%。在总样本中,11.1%患有缺铁性贫血。血清叶酸(<6.6 ng/ml)和维生素B12(<150 pg/ml)缺乏的报告率分别为57.7%和1%,且没有妇女同时存在叶酸和维生素B12缺乏。单因素和多因素分析表明,铁蛋白、血清叶酸和维生素B12水平与贫血无显著相关性。因此,贫血和叶酸缺乏的患病率很高。应考虑采取措施控制这些情况。