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乍得孕妇铁状态评估:母体缺铁对新生儿造血状态的影响。

Evaluation of iron status in Chadian pregnant women: consequences of maternal iron deficiency on the haematopoietic status of newborns.

作者信息

Prual A, Galan P, De Bernis L, Hercberg S

机构信息

Centre de Recherches sur les Anémies Nutritionelles, Institut Scientifique et Technique de l'Alimentation, Paris, France.

出版信息

Trop Geogr Med. 1988 Jan;40(1):1-6.

PMID:3381309
Abstract

An assessment of iron status was performed on 112 pregnant women at delivery (and on their newborns in 70 cases) and on 114 menstruating women in N'Djamena, Chad. Anaemia (according to the haematocrit value) was observed in 25.0% of pregnant women and in 23.7% of menstruating women. Iron deficiency was defined as the combination of a low serum ferritin level (less than or equal to 12 micrograms/l), a low transferrin saturation (less than 16%) and/or a high erythrocyte protoporphyrin (greater than 3 micrograms/g Hb). A moderate increase in the serum ferritin level (between 13 and 50 micrograms/l) associated with a low transferrin saturation and/or a high erythrocyte protoporphyrin concentration indicated iron-deficiency in an inflammatory context. Iron deficiency was present in 66.9% of pregnant women and in 30.7% of menstruating women. Anaemia was associated with iron deficiency in 78.6% of cases in anaemic pregnant women and in 44.4% of cases in anaemic menstruating women. A correlation between maternal and newborn haematopoiesis was found, and some iron parameters in newborns were related to the iron status of mothers.

摘要

对乍得恩贾梅纳的112名分娩孕妇(其中70例还对其新生儿进行了检测)以及114名处于经期的女性进行了铁状态评估。根据血细胞比容值,25.0%的孕妇和23.7%的经期女性存在贫血。铁缺乏定义为血清铁蛋白水平低(小于或等于12微克/升)、转铁蛋白饱和度低(小于16%)和/或红细胞原卟啉高(大于3微克/克血红蛋白)。血清铁蛋白水平适度升高(13至50微克/升之间)且伴有转铁蛋白饱和度低和/或红细胞原卟啉浓度高表明在炎症背景下存在铁缺乏。66.9%的孕妇和30.7%的经期女性存在铁缺乏。贫血孕妇中78.6%的病例以及贫血经期女性中44.4%的病例贫血与铁缺乏相关。发现母体和新生儿造血之间存在相关性,并且新生儿的一些铁参数与母亲的铁状态有关。

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