McGlauchlen Kiley S, Vogel Laura A
Department of Biological Sciences, Illinois State University, Normal, IL 61790-4120, USA.
Microbes Infect. 2003 Nov;5(13):1279-84. doi: 10.1016/j.micinf.2003.09.001.
As individuals age, dysfunction of the immune system leads to an increased incidence of infectious disease. Due to the complex network of cellular interactions and the multi-factorial process of aging, numerous impairments in humoral immunity have been reported. Advances in technology have allowed scientists to begin to identify the molecular mechanisms behind the age-associated decline.
随着个体年龄增长,免疫系统功能障碍导致传染病发病率增加。由于细胞相互作用的复杂网络以及衰老的多因素过程,已有许多关于体液免疫受损的报道。技术进步使科学家能够开始确定与年龄相关衰退背后的分子机制。