Uchiyama Yuji, Ebe Kazutoshi, Kozato Akio, Okada Tomohisa, Sadato Norihiro
Toyota Central R&D Labs., Inc., Nagakute 480-1192, Japan.
Neurosci Lett. 2003 Dec 11;352(3):199-202. doi: 10.1016/j.neulet.2003.08.072.
An important driving skill is the ability to maintain a safe distance from a preceding car. To determine the neural substrates of this skill we performed functional magnetic resonance imaging of simulated driving in 21 subjects. Subjects used a joystick to adjust their own driving speed in order to maintain a constant distance from a preceding car traveling at varying speeds. The task activated multiple brain regions. Activation of the cerebellum may reflect visual feedback during smooth tracking of the preceding car. Co-activation of the basal ganglia, thalamus and premotor cortex is related to movement selection. Activation of a premotor-parietal network is related to visuo-motor co-ordination. Task performance was negatively correlated with anterior cingulate activity, consistent with the role of this region in error detection and response selection.
一项重要的驾驶技能是与前车保持安全距离的能力。为了确定这项技能的神经基础，我们对21名受试者进行了模拟驾驶的功能磁共振成像研究。受试者使用操纵杆来调整自己的驾驶速度，以便与以不同速度行驶的前车保持恒定距离。该任务激活了多个脑区。小脑的激活可能反映了在平稳跟踪前车过程中的视觉反馈。基底神经节、丘脑和运动前区皮质的共同激活与运动选择有关。运动前区-顶叶网络的激活与视觉-运动协调有关。任务表现与前扣带回活动呈负相关，这与该区域在错误检测和反应选择中的作用一致。
