Meijers J C, McMullen B A, Bouma B N
Dept. of Haematology, University Hospital Utrecht, The Netherlands.
Agents Actions Suppl. 1992;38 ( Pt 2):219-30.
In recent years, extensive knowledge has been obtained on the structure/function relationships of blood coagulation proteins. In this overview, we present recent developments on the structure/function relationships of the contact activation proteins: factor XII, high molecular weight kininogen, prekallikrein, and factor XI, with the emphasis on the localization of domains on these proteins that are involved in the interaction with activators, substrates and cofactors.
近年来，人们已获得了关于血液凝固蛋白结构/功能关系的广泛知识。在本综述中，我们介绍了接触激活蛋白（凝血因子XII、高分子量激肽原、前激肽释放酶和凝血因子XI）结构/功能关系的最新进展，重点是这些蛋白上与激活剂、底物和辅因子相互作用相关结构域的定位。
