Borges D R, Kouyoumdjian M
Department of Medicine, Escola Paulista de Medicina, Sao Paulo, Brasil.
Agents Actions Suppl. 1992;38 ( Pt 2):278-84.
Treatment of rat plasma-kallikrein with chloramine T (which does not affect neither its amidolytic activity nor its Mr) impairs the hepatic clearance of the enzyme in a dose-related manner. Preperfusion of the liver with chloramine T before the addition of plasma-kallikrein also diminishes the hepatic clearance of the enzyme.
用氯胺T处理大鼠血浆激肽释放酶（这既不影响其酰胺水解活性，也不影响其相对分子质量）会以剂量相关的方式损害该酶的肝脏清除率。在加入血浆激肽释放酶之前先用氯胺T对肝脏进行预灌注也会降低该酶的肝脏清除率。
