类风湿性关节炎、骨关节炎和银屑病关节炎患者滑液中组织激肽释放酶及α1-抗胰蛋白酶-组织激肽释放酶复合物的测定
Determination of tissue kallikrein and alpha 1-antitrypsin-tissue kallikrein complexes in synovial fluid of patients with rheumatoid, osteo and psoriatic arthritis.
作者信息
Rahman M M, Worthy K, Elson C J, Dieppe P A, Bhoola K D
机构信息
Department of Pharmacology, School of Medical Sciences, University of Bristol.
出版信息
Agents Actions Suppl. 1992;38 ( Pt 3):389-96.
An enzyme-linked immunosorbant assay was developed to determine tissue kallikrein and alpha 1-antitrypsin-tissue kallikrein complexes in pooled synovial fluid of patients with rheumatoid, osteo and psoriatic arthritis. Even though basal values could be determined, the addition of synovial fluid shifted the standard curves for both tissue kallikrein and alpha 1-antitrypsin-tissue kallikrein complex to the right, because of the presence of a novel inhibitor.
开发了一种酶联免疫吸附测定法，以测定类风湿性关节炎、骨关节炎和银屑病关节炎患者滑膜液中的组织激肽释放酶和α1-抗胰蛋白酶-组织激肽释放酶复合物。尽管可以测定基础值，但由于存在一种新型抑制剂，加入滑膜液会使组织激肽释放酶和α1-抗胰蛋白酶-组织激肽释放酶复合物的标准曲线右移。
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