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致敏且受到激发的豚鼠支气管肺泡灌洗(BAL)液中的激肽释放酶样活性。

Kallikrein-like activity in the bronchoalveolar lavage (BAL) fluid of sensitized, challenged guinea-pigs.

作者信息

Featherstone R L, Parry J E, Church M K

机构信息

Clinical Pharmacology, Southampton General Hospital, England.

出版信息

Agents Actions Suppl. 1992;38 ( Pt 3):462-6.

PMID:1462879
Abstract

Sensitization and challenge of guinea-pig airways with aerosols of ovalbumin solution administered through an endotracheal tube leads to a significant increase in kallikrein-like enzyme activity in bronchoalveolar lavage (BAL) fluid. This increase is present up to six hours after challenge and may be related to changes in airways resistance that persist for similar periods.

摘要

通过气管内导管给予卵清蛋白溶液气雾剂对豚鼠气道进行致敏和激发,会导致支气管肺泡灌洗(BAL)液中激肽释放酶样酶活性显著增加。这种增加在激发后长达6小时内都存在,并且可能与持续相似时间段的气道阻力变化有关。

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引用本文的文献

1
Leukocytic cell sources of airway tissue kallikrein.气道组织激肽释放酶的白细胞来源
Am J Physiol Lung Cell Mol Physiol. 2004 Apr;286(4):L734-40. doi: 10.1152/ajplung.00129.2003. Epub 2003 Dec 5.