Schweikhardt R Gary, Piepenbrock Christian, Sledziewski Andrew Z
Expert Rev Mol Diagn. 2003 Nov;3(6):681-3. doi: 10.1586/14737159.3.6.681.
Molecular diagnostics will ultimately have a broad and significant impact on patient treatment. An array of emerging diagnostic tests answer specific and important clinical questions which could offer opportunities for existing and new therapeutics. The development of new diagnostic tests will take time and will require investment in new strategies to find the optimum set of markers, as well as education programs to persuade clinicians, payers and patients to use the new tests and take advantage of the improved therapeutics. Competition among the molecular technologies will be intense; however, it is expected that the most successful companies will exploit synergies between the technologies to develop the most effective molecular diagnostics and, in turn, will improve efficacy of therapeutic practice.
分子诊断最终将对患者治疗产生广泛而重大的影响。一系列新兴诊断测试可回答特定且重要的临床问题，这可能为现有和新的治疗方法提供机会。新诊断测试的开发需要时间，还需要投资于新策略以找到最佳的标志物组合，以及开展教育项目来说服临床医生、支付方和患者使用新测试并利用改进后的治疗方法。分子技术之间的竞争将十分激烈；然而，可以预期，最成功的公司将利用这些技术之间的协同作用来开发最有效的分子诊断方法，进而提高治疗实践的疗效。
