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2至6个月大时听觉皮层的变化及失配负波的发展。

Changes in auditory cortex and the development of mismatch negativity between 2 and 6 months of age.

作者信息

Trainor Laurel, McFadden Melissa, Hodgson Lisa, Darragh Lisa, Barlow Jennifer, Matsos Laura, Sonnadara Ranil

机构信息

Department of Psychology, McMaster University, Hamilton, Canada ON L8S 4B2.

出版信息

Int J Psychophysiol. 2003 Dec;51(1):5-15. doi: 10.1016/s0167-8760(03)00148-x.

DOI:10.1016/s0167-8760(03)00148-x
PMID:14629918
Abstract

Evoked responses to stimulus deviance were compared in infants between 2 and 6 months of age. A deviant stimulus containing a short silent gap occasionally replaced a repeating standard stimulus matched in duration, intensity and approximate spectral content. At two months, the standard stimuli evoked only a positive slow wave, and its amplitude was increased in response to the deviant stimuli. By 6 months, the deviant stimuli evoked an increased negativity at approximately 200 ms, similar to the mismatch negativity (MMN) response in adults. The results are considered with respect to layer-specific cortical maturation during this period.

摘要

对2至6个月大的婴儿对刺激偏差的诱发反应进行了比较。一个包含短暂无声间隙的偏差刺激偶尔会取代一个在持续时间、强度和近似频谱内容上匹配的重复标准刺激。在两个月大时,标准刺激仅诱发一个正向慢波,并且其振幅在对偏差刺激的反应中增加。到6个月大时,偏差刺激在大约200毫秒时诱发了增强的负向波,类似于成年人的失配负波(MMN)反应。结合这一时期特定层的皮质成熟情况对结果进行了考量。

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