Gupta Vijay S, Kumar Alok, Deepak Desh, Khare Anakshi, Khare Naveen K
Department of Chemistry, Lucknow University, -226 007, Lucknow, India.
Phytochemistry. 2003 Dec;64(8):1327-33. doi: 10.1016/s0031-9422(03)00468-0.
Two pregnanes namely desacylkondurangogenin C (1) and deniagenin (3, new) and two new pregnane glycosides designated as denin (5) and marsin (12) have been isolated from chloroform soluble extract of dried stem of Marsdenia roylei. Chemical and spectroscopic evidences are consistent with the structures of deniagenin, denin and marsin as 3beta, 11alpha, l2beta, 14beta, 17beta, 20-hexahydroxy pregn-5-ene; desacylkondurangogenin C-3-O-alpha-D-glucopyranosyl-(1-->4)-O-alpha-L-fucopyranoside and ketocalogenin-3-O-alpha-L-fucopyranoside, respectively.
从牛奶菜干燥茎的氯仿可溶提取物中分离出两种孕甾烷，即去酰基康杜兰皂苷元C（1）和地尼皂苷元（3，新化合物），以及两种新的孕甾烷糖苷，分别命名为地尼苷（5）和马辛苷（12）。化学和光谱证据表明，地尼皂苷元、地尼苷和马辛苷的结构分别为3β，11α，12β，14β，17β，20 - 六羟基孕-5-烯；去酰基康杜兰皂苷元C - 3 - O-α-D-吡喃葡萄糖基-（1→4）-O-α-L-吡喃岩藻糖苷和酮卡洛皂苷元-3 - O-α-L-吡喃岩藻糖苷。
