Lamovec J, Zidar A, Trsinar B, Jancar J
Department of Pathology, Institute of Oncology, Ljubljana, Slovenia.
Am J Surg Pathol. 1992 Dec;16(12):1233-8. doi: 10.1097/00000478-199212000-00010.
A case of inflammatory pseudotumor of the urinary bladder in a 2-year-old child is presented. It was characterized by nodular intravesical growth and massive infiltration of the bladder wall. Microscopically, the lesion showed in its largest part a relatively paucicellular spindle cell growth and a sclerotic appearance with a thin superficial cellular zone resembling granulation tissue. Another morphological characteristic was a marked capillary proliferation revealed by immunohistochemical reactions to factor VIII-associated protein, laminin, and collagen IV. The last feature appears to be an integral part of the process, which most closely resembled fibromatosis of the adult type, a rare pattern of growth in inflammatory pseudotumor.
本文报告了一例2岁儿童膀胱炎性假瘤病例。其特征为膀胱内结节状生长及膀胱壁大量浸润。显微镜下，病变大部分表现为细胞相对稀少的梭形细胞生长及硬化外观，浅表有一薄层类似肉芽组织的细胞区。另一个形态学特征是通过对VIII因子相关蛋白、层粘连蛋白和IV型胶原的免疫组化反应显示出明显的毛细血管增生。最后这一特征似乎是该病变过程的一个组成部分，该病变与成人型纤维瘤病极为相似，是炎性假瘤中一种罕见的生长模式。
