Houben C H, Chan A, Lee K H, Tam Y H, To K F, Cheng W, Yeung C K
Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong.
Pediatr Surg Int. 2007 Aug;23(8):815-9. doi: 10.1007/s00383-007-1885-y. Epub 2007 Apr 19.
Inflammatory myofibroblastic tumor of the bladder is an uncommon condition of unknown neoplastic potential. In adults the tumor is seen in association with instrumentation of the lower genitourinary tract, while in children it appears to run an idiopathic course. Its clinical and radiological presentation in children resembles sarcoma. The case of a 10-year-old girl with inflammatory myofibroblastic tumor is presented, outlining the histological and immunhistochemical features to allow differentiation between sarcomas, the most important differential diagnosis. An outcome meta-analysis of the literature identified 35 cases of inflammatory myofibroblastic tumor in the bladder of children. Conservative surgery is the strategy of choice. There is no evidence of recurrence or metastasis at a median follow up of 1.5 years.
膀胱炎性肌纤维母细胞瘤是一种罕见的疾病，其肿瘤潜能未知。在成人中，该肿瘤与下泌尿生殖道器械操作有关，而在儿童中，它似乎呈特发性病程。其在儿童中的临床和放射学表现类似于肉瘤。本文报告了一名患有炎性肌纤维母细胞瘤的10岁女孩的病例，概述了组织学和免疫组织化学特征，以便与肉瘤进行鉴别，肉瘤是最重要的鉴别诊断。对文献的结果荟萃分析确定了35例儿童膀胱炎性肌纤维母细胞瘤病例。保守手术是首选策略。在中位随访1.5年时，没有复发或转移的证据。
