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[局部麻醉药的硬脑膜下蛛网膜下腔扩散。脊髓麻醉的一种并发症]

[Subdural intra-arachnoid spread of local anesthetics. A complication of spinal anesthesia].

作者信息

Möllmann M, Holst D, Enk D, Lübbesmeyer H, Deitmer T, Lawin P

机构信息

Klinik und Poliklinik für Anästhesiologie und operative Intensivmedizin, Westfälische Wilhelms-Universität Münster.

出版信息

Anaesthesist. 1992 Nov;41(11):685-8.

PMID:1463156
Abstract

Accidental subdural injections and catheterisations are a complication of epidural and spinal anaesthesia. The incidence of subdural spread in myelographies is estimated to be over 10% by the spinal technique. With spinaloscopy in an anatomic human model, we analysed the puncture process and the influence of different needle types on the incidence of subdural injection. We compared 22-gauge Sprotte, Quincke, and 18-gauge Tuohy needles in median and paramedian approaches with various bevel orientations. METHOD. The studies were performed in a preserved and recently expired cadaver donated to the Institut für Anatomie, Westfälische Wilhelms-Universität, Münster. The spinal column from T12 to S1, together with the back musculature (in order to preserve the normal curvature of the spine), were removed from the cadaver. Spinaloscopy was performed with a 4-mm endoscope with a 0 degree optic (Storz, Tuttlingen, Germany). All observations were made in the lumbosacral region of the dissected preparation. The endoscope was inserted from the caudal end of the spinal canal and, depending on the observations being made, the spinal canal was filled with air or artificial cerebrospinal fluid (CSF). To obtain information on the distribution of local anaesthetics injected into the subarachnoid space, 0.5% bupivacaine was coloured with a small amount of 1% methylene blue. The distribution of the coloured anaesthetic was clearly visible during and after injection. RESULTS. Needle insertion: Multiple observations were made using median or paramedian advancement of the needle into the spinal canal. With all needles, including the pencil-point, we saw an unexpected inward movement of the dura to the epidural space before penetration. This dural movement was independent of the direction of the dural fibres in the lumbar area. Distribution of local anaesthetics: Our observations indicate that difficulty with injecting drugs occurred when needle insertion was stopped too close to the dura, especially with the Sprotte needle. After manually registered penetration of the dura, the lateral opening of the needle only partially penetrates the dura. This allows CSF to appear in the needle hub, and injection into the vertical subdural space is possible. In all cases with the Sprotte needle, we could reproduce deposition of methylene-blue-coloured local anaesthetics into the subdural space. With the Quincke and Thuohy needles, it was not possible to deposit local anaesthetics into the subdural space in this model. CONCLUSION. Spinaloscopy was done in a non-fixated anatomic preparation of a spinal column with a 4-mm, 0 degree endoscope. From these observations we conclude that both manually registered penetration of the dural and the appearance of CSF in the needle hub can mimic correct needle position. Especially with the lateral opening of the Sprotte needle, deposition of local anaesthetics in the subdural space is possible.

摘要

意外硬膜下注射和置管是硬膜外麻醉和脊髓麻醉的一种并发症。据估计,采用脊髓造影技术经脊髓途径时硬膜下扩散的发生率超过10%。我们利用人体解剖模型进行脊柱内镜检查,分析了穿刺过程以及不同类型穿刺针斜面方向对硬膜下注射发生率的影响。我们比较了22号Sprotte针、Quincke针和18号Tuohy针在正中及旁正中进针途径、不同斜面方向的情况。方法:研究在捐赠给明斯特威斯特法伦威廉姆斯大学解剖学研究所的一具保存完好且近期死亡的尸体上进行。从尸体上取下T12至S1的脊柱以及背部肌肉组织(以保持脊柱的正常曲度)。使用带有0度视角的4毫米内镜(德国图特林根的史托斯公司生产)进行脊柱内镜检查。所有观察均在解剖标本的腰骶部进行。内镜从椎管尾端插入,根据观察需要,椎管内充入空气或人工脑脊液。为获取注入蛛网膜下腔的局部麻醉药分布情况,将0.5%布比卡因用少量1%亚甲蓝染色。染色后的麻醉药在注射过程中和注射后均可清晰看到其分布情况。结果:进针情况:使用多种进针方式将针经正中或旁正中推进至椎管内进行多次观察。使用所有穿刺针,包括笔尖式穿刺针,我们都观察到在穿透硬膜之前硬脊膜意外向硬膜外间隙内移动。这种硬脊膜移动与腰部硬脊膜纤维方向无关。局部麻醉药分布情况:我们的观察表明,当进针时过于靠近硬脊膜就停止进针时,尤其是使用Sprotte针时,会出现注药困难。在手动记录硬膜穿透后,针的侧孔仅部分穿透硬膜。这使得脑脊液出现在针座内,从而有可能将药物注入垂直的硬膜下间隙。在所有使用Sprotte针的情况下,我们都能重现亚甲蓝染色的局部麻醉药在硬膜下间隙的沉积情况。而在该模型中,使用Quincke针和Tuohy针时,无法将局部麻醉药沉积到硬膜下间隙。结论:使用4毫米、0度视角的内镜在一具未固定的脊柱解剖标本上进行了脊柱内镜检查。根据这些观察结果,我们得出结论,手动记录的硬膜穿透以及脑脊液出现在针座内都可能模拟正确的针位置。特别是Sprotte针的侧孔,有可能将局部麻醉药沉积到硬膜下间隙。

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