Huang W, Cade J F, Pain M C
Department of Thoracic Medicine, Royal Melbourne Hospital, Victoria, Australia.
Anaesth Intensive Care. 1992 Nov;20(4):456-9. doi: 10.1177/0310057X9202000410.
The oxygen tension for half saturation (P50) was determined for venous blood in thirteen patients with the adult respiratory distress syndrome undergoing intensive therapy. The mean value for P50 was found to be significantly lower than the value found in ten normal control subjects (22.9 mmHg and 26.7 mmHg respectively; t = 3.03, P < 0.01). The extent of reduction in P50 was not related to serum phosphate level nor was it a predictor of short-term outcome. It is unlikely that the slight left-shifted oxygen-haemoglobin dissociation curve contributes in a major way to an oxygen delivery deficiency and its cause is unexplained.
对13例接受强化治疗的成人呼吸窘迫综合征患者的静脉血测定了半数饱和氧分压（P50）。发现P50的平均值显著低于10名正常对照者的值（分别为22.9 mmHg和26.7 mmHg；t = 3.03，P < 0.01）。P50降低的程度与血清磷酸盐水平无关，也不是短期预后的预测指标。氧合血红蛋白解离曲线轻度左移不太可能在很大程度上导致氧输送不足，其原因尚不清楚。
