Altin R, Erol Y, Ozdemir H, Kart L, Ozen O, Mahmutyazyeyoglu K
Zonguldak Karaelmas University, Department of Pulmonology, Faculty of Medicine, Kozlu, 67600, Zonguldak, Turkey.
Monaldi Arch Chest Dis. 2003 Apr-Jun;59(2):166-8.
Primary neoplasms of the pleura are rare tumors and the majority are generally mesotheliomas. Mesotheliomas are either localized and mostly benign, or diffuse and uniformly malignant neoplasms. Localised benign pulmonary mesothelioma (solitary fibrous tumor of the pleura) are originally thought to be a variant of diffuse pleural mesothelioma because they consists of a spindle cell stroma associated with branching tubular structures lined by cuboidal cells. Our case which is reported below shows the clinical spectrum of the more common benign variant. Clinical differential diagnosis of benign and malign mesotheliomas is not clear. Complete surgical resection is the preferred treatment for both types and usually curative with the benign mesothelioma. The localised pleural variant is benign in most cases, and it is even less common, constituting only 10% of all mesotheliomas [1]. The importance of localised benign mesothelioma is that it is almost impossible to differentiate from a malignant neoplasm preoperatively and it may occasionally recur, sometimes with a malignant change.
胸膜原发性肿瘤是罕见肿瘤,大多数通常为间皮瘤。间皮瘤要么是局限性的,大多为良性,要么是弥漫性的,均为恶性肿瘤。局限性良性肺间皮瘤(胸膜孤立性纤维瘤)最初被认为是弥漫性胸膜间皮瘤的一种变体,因为它们由梭形细胞基质组成,伴有由立方细胞衬里的分支管状结构。下面报告的我们的病例展示了更常见的良性变体的临床谱。良性和恶性间皮瘤的临床鉴别诊断尚不清楚。完整的手术切除是这两种类型的首选治疗方法,对良性间皮瘤通常具有治愈性。局限性胸膜变体在大多数情况下是良性的,而且更为少见,仅占所有间皮瘤的10%[1]。局限性良性间皮瘤的重要性在于术前几乎不可能与恶性肿瘤区分开来,并且它可能偶尔复发,有时会发生恶性变化。