Nassiopoulos K, Rostan O, Petropoulos P
Hôpital Monney Châtel-Saint-Denis.
Rev Med Suisse Romande. 1993 Aug;113(8):603-6.
Pleural mesotheliomas are uncommon tumors that can be classified as localized fibrous or diffuse malignant. The frequency in the general population is low and, as it concern the diffuse malignant type, exposure to asbestos, significantly increases the incidence. The most common symptoms are chest pain, short of breath and cough and the roentgenological findings are solitary or multiple pleural nodular lesions. The fibrous type can be excised and recurrence rarely occurs, but the malignant type does not respond either to chemotherapy or to radiotherapy and surgical measures offer only palliation. Thoracoscopy is a possibility of surgical excision in a case of localized mesothelioma and in case of diffuse type it contributes to the diagnostic yield, the open surgical procedures to be considered only in functionally operable patients.
胸膜间皮瘤是一种罕见的肿瘤，可分为局限性纤维性或弥漫性恶性。一般人群中的发病率较低，就弥漫性恶性类型而言，接触石棉会显著增加发病率。最常见的症状是胸痛、气短和咳嗽，影像学表现为孤立性或多发性胸膜结节性病变。纤维性类型可以切除，很少复发，但恶性类型对化疗或放疗均无反应，手术措施仅能提供姑息治疗。对于局限性间皮瘤病例，胸腔镜检查是手术切除的一种选择；对于弥漫性类型，胸腔镜检查有助于提高诊断率，开放性手术仅适用于功能上可手术的患者。
