Long S N, Michieletto A, Anderson T J, Williams A, Knottenbelt C M
Department of Veterinary Clinical Studies, University of Glasgow Veterinary School, Bearsden Road, Bearsden, Glasgow G61 1QH.
J Small Anim Pract. 2003 Nov;44(11):497-502. doi: 10.1111/j.1748-5827.2003.tb00110.x.
Pituitary apoplexy is a syndrome which has been described in humans caused by acute haemorrhage or infarction within a pituitary tumour or a non-tumorous pituitary gland. This report describes the authors' observations of a dog in which vomiting, visual disturbances, seizures, altered consciousness and diencephalic dysfunction occurred in association with haemorrhage originating from a pituitary macroadenoma. The clinical signs were thought to be consistent with disruption of the hypothalamus and brainstem, together with raised intracranial pressure due to intraventricular haemorrhage. These signs, and the pathological findings, bear a striking resemblance to those associated with the syndrome of pituitary apoplexy, seen in humans.
垂体卒中是一种在人类中已被描述的综合征,由垂体肿瘤或非肿瘤性垂体腺内的急性出血或梗死引起。本报告描述了作者对一只狗的观察,该狗出现呕吐、视觉障碍、癫痫发作、意识改变和间脑功能障碍,同时伴有源自垂体大腺瘤的出血。临床症状被认为与下丘脑和脑干的破坏一致,同时由于脑室内出血导致颅内压升高。这些症状和病理发现与人类垂体卒中综合征相关的症状和发现极为相似。