Kopera Daisy
Department of Dermatology, University of Graz, Graz, Austria.
Int J Dermatol. 2003 Nov;42(11):905-8. doi: 10.1046/j.1365-4362.2003.01994.x.
Various approaches have been taken in the management of verrucae vulgares, but there is still no first-choice treatment. Thus, a study was designed to evaluate the efficacy of a flashlamp-pumped pulsed dye laser (FPDL) in the treatment of verrucae vulgares.
Within 18 months, 134 patients with recalcitrant or untreated verrucae vulgares on their hands or feet, or in other sites, were exposed to a 585-nm FPDL every 3.26 weeks. The following parameters were used: energy density, 8 J/cm2; spot size, 7 mm; pulse duration, 450 micro s. Concomitant topical treatment was not recommended.
Eight patients were lost to follow-up. The data of 126 patients were evaluated. Up to eight laser treatments led to total remission in 62.69% of patients and partial remission in 21.42%; 9.52% did not respond to this type of management; 6.34% of patients classified the method as too painful and withdrew after the first one or two treatments. In a median follow-up period of 5.38 months (2-16 months), one relapse occurred.
FPDL is safe and effective for the removal or reduction of verrucae vulgares, and requires less patient compliance compared with other treatment options.
寻常疣的治疗已采用了多种方法，但仍没有首选治疗方法。因此，设计了一项研究来评估闪光灯泵浦脉冲染料激光（FPDL）治疗寻常疣的疗效。
在18个月内，134例手部、足部或其他部位患有顽固性或未经治疗的寻常疣患者，每3.26周接受一次585纳米的FPDL治疗。使用以下参数：能量密度8焦/平方厘米；光斑大小7毫米；脉冲持续时间450微秒。不建议同时进行局部治疗。
8例患者失访。对126例患者的数据进行了评估。多达8次激光治疗使62.69%的患者完全缓解，21.42%的患者部分缓解；9.52%的患者对这种治疗方式无反应；6.34%的患者认为该方法过于疼痛，在接受一两次治疗后退出。在中位随访期5.38个月（2 - 16个月）内，发生了1例复发。
FPDL对于去除或减少寻常疣是安全有效的，与其他治疗选择相比，患者依从性要求较低。
